I admit (and did before) that I
never had any interest in learning, making sense and/or understand anything in
what I’m calling the “guess-science”, for the most part I follow what my “common
logic” tells me what makes any sense.
I have, however been in email
contact both with important bio-engineers and even people at the FDA who for
their own reasons simply tell me that they are Mr. I, or Mr. B or whatever, I
guess because they never want to risk to be (mis-)quoted in what they say in anything
they decide to give their inputs.
So what I’m writing here comes from
one of these “nobody” involved in the TBI recovery research and given that it
makes sense to me I quote it almost literally (and in Italic).
I explain something basic to you about disease, in
particular complex diseases having to do with brain injury or degeneration.
The outcome of a particular stroke or TBI event, typically kills brain
cells within a central zone, and rather than killing cells in the outer zone,
or penumbra, does inhibit their activity. What Enbrel seems to be doing
is to be removing this inhibition, most likely on synapses because of the
rapidity of action. This has not been approached by previous treatments.
No current treatment is going to bring back the dead cells, which is why
there is much interest in stem cell research, which aspires to do this.
Enbrel, on the other hand, appears to remove cell inhibition
in the penumbra. How well someone responds, is determined by how big the
central, as distinct from the outer, zone, is. If a large central zone is
damaged, Enbrel outcomes appear to be telling to the field that the outer,
inhibited zone is often larger than previously suspected.
This type of unknown aspect of many of these diseases is why
outcomes vary. It is a principle applying to all conditions in which research
that is more basic is required, but it rarely is looked at properly because
funding in general is scarce. A positive outcome in rheumatoid arthritis,
the biggest use to which Enbrel is put, is that about 70%, for essentially the
same reason.
And this is why my injured logic and
intelligence can’t let me stop hoping that sooner than later somebody will
figure out that this “off-label” use of Enbrel can truly save our country from
its financial difficulties and put back to work the (too) many victims of TBI
who can’t wait for the already existing solution to be widely adopted by our government and the
entire US guess-science population.
Sadly too many MD have already
attempted to give logic to their refusal to treat me, but if anyone might have
a word in my support I ask to please leave their comments.
No comments:
Post a Comment